Searchable abstracts of presentations at key conferences in endocrinology

ea0020p69 | Thyroid | ECE2009

Diagnostic ability of computed tomography to assess Graves ophthalmopathy

Dragomir Adina , Dumitrascu Anda , Marinescu Ileana , Dumitrache Constantin , Dalea Anca , Hristea Ruxandra , Iconaru Laura , Oros Sabina

Objective: CT findings indicating that a patient is at risk for developing optic neuropathy are worth- while observations.Aim: The aim of our study was to determine the utility of CT imaging in identifying patients at risk for optic neuropathy and to compare quantifiable nonvolumetric CT data from a large series of orbits with Graves ophthalmopathy.Method: A total of 226 patients (452 orbits), 175 women (350 orbits) and 51 men (102...

ea0022p437 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

RET mutation screening in multiple endocrine neoplasia type 2 (MEN2) and medullary thyroid carcinoma patients (MTC) in Romania

Loreta Paun Diana , Radian Serban , Iconaru Laura , Badiu Corin , Grigorie Daniel , Marinescu Ileana , Coculescu Mihai , Dumitrache Constantin

Background: According to current guidelines, RET mutation screening is indicated for MEN2 and familial MTC (FMTC) kindreds, as well as for apparently sporadic MTC patients.Aim: To investigate RET mutations in Romanian MEN2, FMTC and sporadic MTC cases.Patients and methods: RET mutation screening was performed by high-resolution melting analysis followed by direct sequencing of PCR products of exons 10-11 in 7 MEN2A families, 2 FMTC...